Monday, 8 September 2008

Brandy Readies Human After Four-Year Hiatus: 'I Never Wanna Leave For That Long Again'





It's been a whole George W. Bush presidential term since Brandy's last album, Afrodisiac. Back then, her daughter was merely a baby � heck, her pal Ray J was but a baby in some people's eyes � and the music business was a hale different animal.


"It feels so great to be back on the scene," she said last week on the set of her video for "Right Here (Departed)." She was acquiring her feet wet over again in social movement of the camera.





"I went through a struggle, and I truly needed to get myself together and connect with my aim, which is music," she explained of the abatement, the longest of her 14-year calling. "Music is all I know. ... To be on this determine today, I feel very blessed for the second chance and for the opportunity, my record troupe believing in me and everybody here just screening me so much sexual love and financial support. My fans. It only feels beneficial to be back, and I never wanna leave for that long again."


A decade ago, the singer released her most commercially successful LP, Never Say Never. It was a triumph that undisputedly skint her out of the pack that included a talented consortium of one-named women such as Mya and Monica. Over the years, Brandy has worked less and less with the drive force in arrears that album's production, Rodney Jerkins. Their differences became evident on the last album, Afrodisiac, when Timbaland replaced Darkchild as her go-to guy. But Jerkins is gage for the new album, Human.


"Well, the chemistry brought Rodney and I back together," she explained. "I mean, it's a chemistry that's undeniable, it's witching. I think it's our responsibility to make music together. I think it's our contribution to the world. I mean, I think that we take a seat, a lane, and we have mass out in that location that love seeing us working together, and again, I'm simply blessed to be back working with him. 'Right Here (Departed)' was the first sung that I heard that Rodney treasured to do for with me, and that was the beginning song I did with him. Our reconnect � and it's our first-class honours degree single. So our have this clock time has been very wizardly. Our sound is a little fleck different from our old sound, only we ar back, and I'm ne'er leaving Rodney again, and I bob Hope he never leaves me."


"The music brought it back together," Jerkins agreed. "I mean, at the end of the day, we wanted to do something for the fans and show the world that we got this chemistry that can't be denied and can't be stopped-up. The earth is gonna get it when they hear the album. The album just reflects on everything she's been through in the last eighter to 10 years and how she came tabu of it and how she's potent and she's a woman. I'm just now here to do my thing and to support it.


"It's definitely a big pop-sounding album, international sounding. But she hits a little spot on the country face," he added about the rest of his work on the album. "Vocally, she does a bunch of niggling country twangs with her voice. We kid around, we jape around that the next album is gonna be country. We're both gonna step out and do some nation music. But we're rather tapping into it, to show that you potty mix that sound with urban and R&B and hip-hop. It's just music, and good music lives."


Brandy � wHO, believe it or non, will turn 30 succeeding year � described the album as more mature but more pop than she's of all time gone.


"I cherished to make it for everybody, non just urban but every race, every color, every creed, any," she said. "I just now wanted to make a universal album, and that's what we did, and we effected that. And I'm really excited some it, it's out November 11, and we launch it November 10 with Oprah, so I'm really excited.


"The record album title is called Human," she continued. "I wrote the claim track to the album, and basically what that song is about is forgiveness. Mistakes are gonna be made; we're all gonna create them. One of the lines in the song is 'I'm only human, I might just evidence a lie/ I'm only human, I'm an angel in disguise.' There's another song on the album called 'Warm It Up With Love.' I'm talking around how the whole world is freezing, [but] we just motive to fond the world up with love. [Then there's] 'Piano Man,' where I go to this piano man and require him to play a song of love, play a song about heartbreak, so we can have the unanimous world singing tonight. It's really some cool concepts on the album."


The individual and its video ar about being there for a loved one.


"You can buoy take it like you're talking approximately a mother and a daughter, a sister, blood brother, girlfriend, whatever � it's universal in that way," she aforementioned. "And the video concept is me crossing over to the other side and advent back into my family's life. Just popping up everywhere, but singing to them, and it's [got] an I Am Legend feel. Sometimes you go steady me on the street by myself completely, and it's pretty cool. Little X is directing it. I'm actually excited about it. I just hope it turns out keen and everybody loves it."


Jerkins appears in the video, as does Ray J.


"I always strain to get in it when I can," aforementioned Ray, wHO described his older sibling's return as "a long time approaching." "If it don't make sense, then I don't [do it]. But she called me down. I canceled all my plans � I had a show to do somewhere else, merely I'm gonna be here for this video 'cause I know how important it is for her, and I know just how important it is to be around and just support her and whatever she needs, so I'm here for her."







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Friday, 29 August 2008

Prototype Test For Predicting Clinical Outcome For Melanoma Patients - Gene Signature Prognostication Of Rapid Progression From Stage III To Stage IV

�Investigators from the Melbourne Center of the outside Ludwig Institute for Cancer Research (LICR) and Pacific Edge Biotchnology Ltd today reported that they hold developed a test to predict whether a patient will progression rapidly from Stage III melanoma to metastatic Stage IV cancer and death.


More than 70% of patients with Stage III melanoma - melanoma that has spread to the lymph nodes - testament typically have a rapid time to progression (TTP) to Stage IV malignant melanoma, and put across away inside five old age of their diagnosis. However, the remaining

The LICR Melbourne squad, together with collaborators from Pacific Edge Biotechnology Limited in New Zealand, has developed a prototype test that can buoy distinguish 'tween these deuce patient subtypes with 85-90% accuracy. However, the team cautions that these findings must be validated in a bigger number of patients earlier the test can be applied routinely as a prognostic dick.


According to the senior author of the study, LICR's Professor Jonathan Cebon, M.D., the predictive test could assist patients and their health care teams in devising treatment decisions. Perhaps to the highest degree importantly, organism able to distinguish betwixt the subtypes could get a tremendous impact on the developing of new melanoma therapies. "One of the major problems we have in clinical trials for new melanoma therapies is that we can't identify the people wHO are going to own a slower disease advance no matter what they receive in a clinical trial," says Professor Cebon. "When new treatments are tested it is necessary to present clinical benefit by comparison patients world Health Organization receive the new therapy with those who do not. Although patients might all have the same type of cancers, at that place can be big differences in their survival simply because their cancers do differently - and this may make nothing to do with the intervention. If we are able-bodied to key out the good players and the bad players upfront, it becomes a whole lot easier figuring out whether good results are due to the new treatment or not. Most importantly far fewer patients would be needed for the clinical trials. It's partly because we can't clinically identify subtypes of patients that we suffer to do very big and very expensive trials. And, of course, this increases the time it takes to test the clinical benefit of potential drop new therapies."


The joint Australian/New Zealand team used microarrays to measure the expression of more than 30,000 genes in lymph knob sections taken from 29 patients with Stage III melanoma. There were 2,140 genes differentially expressed in the sections from people world Health Organization had already had a "poor" outcome (average TTP of just four months) and patients that had had a "good" outcome (average TTP of 40+ months). Using statistical analyses, the team identified 21 genes that could be used to differentiate between the deuce subtypes of patients in the retrospective analysis. This gene signature was then used to prospectively examine another 10 patients, with the clinical outcome for nine of the 10 (90%) patients proving to be predicted accurately. The one patient who was incorrectly predicted to have a "good" prognosis did have a rapid TTP to Stage IV. However, this patient role went on to feature a drawn-out survival of six years. The squad also applied the test to promulgated data sets and showed they could get a prediction truth of 85%, event though data was not uncommitted for all 21 genes in the published literature.


This discipline was conducted under the auspices of the Hilton - Ludwig Cancer Metastasis Initiative. It was light-emitting diode by investigators from: LICR Melbourne Center Austin Health, Melbourne, Australia; Department of Biochemistry, University of Otago, Otago, New Zealand; Pacific Edge Biotechnology Limited, Dunedin, New Zealand, and; Department of Statistics, University of Auckland, Auckland, New Zealand.


Source - Sarah L. White
Ludwig Institute for Cancer Research


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Tuesday, 19 August 2008

Heidi & Spencer to Marry on Live TV


If you think Heidi Montag and Spencer Pratt are slowing down their quest for world say-so, think again.



On Monday, Heidi confirmed in an question with Extra that she and Pratt plan to marry on live TV, saying, "I'm just waiting for that big ring!"

Montag also aforesaid that on that point could be little "Speidis" hamming it up for the cameras in the future (Can you imagine?).

"I want kids...eventually," she says. Over the weekend, The Hills co-star, Audrina Patridge, open up almost her frosty relationship with Montag, telltale, "You know, I don't have a problem with her...That's 'tween her and Lauren [Conrad]."

Heidi confirms there's no problem between herself and Audrina, saying, "We hang kO'd. We're friends...I love Audrina."



When asked if she had any plans to leave The Hills, Montag aforesaid, "No, where would I go?"



Well, at least she knows it!



Tune in to Extra tonight to see the full interview!









Would you watch Heidi and Spencer's wedding on live TV?

Sure, I love a good trainwreck!
Ugh, No! Enough with them already!










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Saturday, 9 August 2008

Int and The Movement

Int and The Movement   
Artist: Int and The Movement

   Genre(s): 
Other
   



Discography:


Version 1.0   
 Version 1.0

   Year: 2004   
Tracks: 4




 





Terri Clark

Tuesday, 1 July 2008

Dannii Minogue 'Unhappy' at Cheryl Cole's X Factor Pay Deal

Dannii Minogue is said to be "not happy" at new X Factor judge Cheryl Cole's �800,000 ($1.6m) pay packet -- because it's only �100,000 ($200k) less than hers.


Dannii, the sister of Kylie Minogue, feels there should be a bigger pay gap between the pair and she should be earning nearer former judge Sharon Osbourne's �1.5m ($3m) salary.


A source tells Britain's Daily Mirror newspaper, "She's not happy that Cheryl is on �800,000, just �100,000 less than her. She feels there should be a bigger gap and, with Sharon gone, she should be earning nearer her �1.5m pay packet."


And because of the age difference between the pair -- Chery's 24; and Dannii's 36 -- there's fierce competition between the two ladies to look the best -- and insiders reckon Dannii has had work done.


The source adds, "Dannii walked into Arsenal's Emirates stadium for the auditions and you could tell she'd put in a lot of work into looking good. She knows there's a younger, more successful, more attractive kid on the block and they will both be fighting for attention.


"Dannii's face seems a lot tighter than last year and everyone is gossiping that she's had a bit of work done.


"She's 36 and Cheryl is just 24 and she's desperate not to be cast as the older Sharon Osbourne type -- she wants to be Cheryl's equal. But it isn't working out like that."


And Dannii is also said to be feeling "eclipsed" by the Girls Aloud singer -- because she's constantly winning praise from Simon Cowell, who's calling her the 'new Cilla Black'.


"She has a great empathy for those auditioning because she has been there herself," the source adds.


"She has had a tough time and knows what it is like to go throught his process. Simon is delighted with how things have gone.


"He is calling her the 'new Cilla Black'. She has that touch that connects with people. She is a natural fit to the show and makes Dannii somewhat redundant.


"Louis and Cheryl get on like a house on fire as he managed Girls Aloud. He has never really got on with Dannii so that has made her feel even more isolated.


"It's ironic that last year Sharon felt under threat from the younger rival when Dannii arrived. Now it is Dannii who is under pressure herself."




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Monday, 30 June 2008

Shirley Bassey out of Nelson Mandela birthday concert

Dame Shirley Bassey has pulled out of the forthcoming Nelson Mandela tribute concert, set to take place at London's Hyde Park on Friday (June 27) to mark his 90th birthday.

Bassey had emergency stomach surgery last month, but was expected to recover in time for the performance. However, her surgeon has advised her not to travel, reports BBC News, prompting her cancellation.

Amy Winehouse is still scheduled to appear at the bash, despite being diagnosed as suffering from the lung disease emphysema.

Queen, Annie Lennox and Simple Minds are among the other acts set to play at the show.

John Coltrane with Johnny Hartman

John Coltrane with Johnny Hartman   
Artist: John Coltrane with Johnny Hartman

   Genre(s): 
Pop
   



Discography:


John Coltrane and Johnny Hartman   
 John Coltrane and Johnny Hartman

   Year: 1995   
Tracks: 6